3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2608 | CHIR-98014 | CHIR 98014,CT98014,CHIR98014 | FGFR , GSK-3 , Src , S6 Kinase |
CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo. | |||
T3074 | CHIR 98024 | CHIR98014 | GSK-3 , S6 Kinase |
CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. | |||
T3074L | CHIR98014 HCl (252935-94-7 free base) | CT-98014,CHIR-98014 hydrochloride,CHIR-98014,CHIR98014 HCl,CHIR98014,CHIR 98014 | |
CHIR98014 is a reversible, cell-permeable inhibitor of GSK3α and GSK3β (IC50s: 0.65 and 0.58 nM). Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50: 106 nM), potentiates insulin-dependent... |